{"id":871,"date":"2015-01-26T11:09:36","date_gmt":"2015-01-26T11:09:36","guid":{"rendered":"http:\/\/lupusgalicia.org\/?p=871"},"modified":"2015-01-26T11:09:36","modified_gmt":"2015-01-26T11:09:36","slug":"un-estudio-sugiere-que-bacterias-intestinales-alteradas-podrian-mitigar-el-lupus","status":"publish","type":"post","link":"https:\/\/lupusgalicia.org\/?p=871","title":{"rendered":"Un estudio sugiere que bacterias intestinales alteradas podr\u00edan mitigar el lupus"},"content":{"rendered":"<h1 style=\"text-align: center;\"><span style=\"color: #800080;\">Seg\u00fan una investigaci\u00f3n publicada en <em>Applied and Environmental Microbiology<\/em>, se ha visto que en estudios realzados a ratones, algunas especies de Lactobacillus, (com\u00fan en cultivos de yogur), parece que mitigan los s\u00edntomas del lupus, mientras un tipo de Clostridia, Lachnospiraceae, se relaciona con el empeoramiento.<\/span><\/h1>\n<p><em>\u00abNuestros resultados sugieren que la misma investigaci\u00f3n deber\u00eda realizarse en sujetos humanos con lupus\u00bb,<\/em> dice el investigador principal Xin Luo de Virginia Tech, en Blacksburg, VA.<\/p>\n<p>En el estudio, los investigadores mostraron primero en\u00a0modelos de rat\u00f3n con lupus ten\u00edan niveles m\u00e1s altos de Lachnospiraceae (un tipo de Clostridia), y menor Lactobacillus que los ratones de control.\u00a0Tambi\u00e9n compararon ratones machos y hembras, y encontraron que las diferencias estaban presentes s\u00f3lo en las mujeres.\u00a0Estos resultados sugieren que las bacterias intestinales pueden influir en el lupus, una enfermedad que es nueve veces m\u00e1s frecuente en las mujeres como en los hombres, dice el primer autor Husen Zhang.<\/p>\n<p>Tambi\u00e9n supervisaron la microbi\u00f3tica intestinal en el tiempo, tanto en ratones con lupus ycomo en los de control, y se encontr\u00f3 que en el primero, los clostridios aumentaron en ambas etapas, tempranas y tard\u00edas, de la enfermedad.<\/p>\n<p>La investigaci\u00f3n sugiere, <span style=\"text-decoration: underline;\">pero no prueba<\/span>\u00a0, que la alteraci\u00f3n de la flora intestinal podr\u00eda mitigar lupus.\u00a0Sin embargo, Luo sugiere que las personas con lupus deben comer probi\u00f3ticos que contengan Lactobacillus, tales como yogures, para reducir los brotes de lupus.\u00a0De manera m\u00e1s general, \u00ab<em>El uso de los probi\u00f3ticos, prebi\u00f3ticos y antibi\u00f3ticos\u00a0tiene el potencial de alterar la disbiosis microbi\u00f3tica, que a su vez podr\u00eda mejorar los s\u00edntomas del lupus \u00ab<\/em>, dice el co-investigador principal Husen Zhang.\u00a0En \u00faltima instancia, dice Luo, un trasplante fecal podr\u00eda ser valioso como un tratamiento para el lupus.<\/p>\n<p>\u00ab<em>Nos inspiramos en parte para llevar a cabo esta investigaci\u00f3n por un estudio sobre el tipo de diabetes tipo1, que encontr\u00f3 que el que la enfermedad depende de la microbi\u00f3tica intestinal<\/em> \u00ab, dice Zhang.\u00a0\u00ab<em>Como la diabetes tipo 1, lupus es una enfermedad autoinmune que es a\u00fan m\u00e1s frecuente [que la diabetes tipo 1] en las mujeres<\/em>.\u00bb<\/p>\n<p>&nbsp;<\/p>\n<p>Informaci\u00f3n aparecida en \u00a0<a href=\"http:\/\/www.medicalnewstoday.com\/releases\/284170.php\">Medicalnews<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Seg\u00fan una investigaci\u00f3n publicada en Applied and Environmental Microbiology, se ha visto que en estudios realzados a ratones, algunas especies de Lactobacillus, (com\u00fan en cultivos de yogur), parece que mitigan los s\u00edntomas del lupus, mientras un tipo de Clostridia, Lachnospiraceae, se relaciona con el empeoramiento. \u00abNuestros resultados sugieren que la misma investigaci\u00f3n deber\u00eda realizarse en [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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