{"id":2517,"date":"2020-11-10T21:21:13","date_gmt":"2020-11-10T19:21:13","guid":{"rendered":"http:\/\/lupusgalicia.org\/?p=2517"},"modified":"2020-11-10T21:21:17","modified_gmt":"2020-11-10T19:21:17","slug":"coronavirus-cuatro-fenotipos-y-su-riesgo","status":"publish","type":"post","link":"https:\/\/lupusgalicia.org\/?p=2517","title":{"rendered":"Coronavirus: cuatro fenotipos y su riesgo"},"content":{"rendered":"\n<p class=\"has-vivid-purple-color has-text-color has-medium-font-size wp-block-paragraph\">Los m\u00e9dicos internistas de la Sociedad Espa\u00f1ola de Medicina Interna (SEMI) han detectado cu\u00e1les son los s\u00edntomas que auguran un buen o mal pron\u00f3stico en la evoluci\u00f3n cl\u00ednica del paciente con COVID19. Los resultados preliminares han sido publicados en <em>Journal of Clinical Medicine\u00a0<\/em>bajo el t\u00edtulo\u00a0<a rel=\"noreferrer noopener\" href=\"https:\/\/www.mdpi.com\/2077-0383\/9\/11\/3488\" target=\"_blank\">\u201cPredicting Clinical Outcome with Phenotypic Clusters in COVID-19 Pneumonia: An Analysis of 12.066 Hospitalized Patients from the Spanish Registry SEMI-COVID-19\u201d<\/a><\/p>\n\n\n\n<p class=\"has-normal-font-size wp-block-paragraph\">Se ha identificado, establecido y caracterizado\u00a0<strong>cuatro grandes grupos fenot\u00edpicos de pacientes COVID-19, uno de ellos especialmente con alto riesgo de ingreso en UCI , mal pron\u00f3stico y mortalidad  y otro, por el contrario, asociado a buen pron\u00f3stico y con bajo riesgo de muerte.<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"has-text-align-center has-medium-font-size wp-block-paragraph\"><strong>Fiebre, tos y disnea mala combinaci\u00f3n<\/strong> <\/p>\n\n\n\n<p class=\"has-text-align-center has-medium-font-size wp-block-paragraph\"><strong>Falta de gusto y de olfato mejor pron\u00f3stico<\/strong><\/p>\n\n\n\n<p class=\"has-vivid-purple-color has-text-color has-normal-font-size wp-block-paragraph\"><strong>Seg\u00fan Manuel Rubio-Rivas, m\u00e9dico internista miembro de SEMI y primer firmante del estudio,<\/strong>\u00a0<strong>los pacientes con peor pron\u00f3stico son los que presentan la tr\u00edada cl\u00e1sica de fiebre, tos y disnea, junto con v\u00f3mitos y diarreas.<\/strong> <\/p>\n\n\n\n<p class=\"has-medium-font-size wp-block-paragraph\"><strong>\u00abLos cuatro grupos fenot\u00edpicos identificados pueden permitir a los facultativos que atienden estos enfermos detectar, solo con los s\u00edntomas presentes al inicio, aquel subgrupo de pacientes con peor pron\u00f3stico\u00a0<\/strong>frente a aquellos con mejor pron\u00f3stico, para poder instaurar las medidas de tratamiento m\u00e1s apropiadas en cada caso, en una medicina de mayor precisi\u00f3n\u00bb, explica Rubio<\/p>\n\n\n\n<p class=\"has-text-align-center has-vivid-purple-color has-text-color has-normal-font-size wp-block-paragraph\"><strong>Cuatro fenotipos<\/strong><\/p>\n\n\n\n<p class=\"has-normal-font-size wp-block-paragraph\">El primer fenotipo present\u00f3 la mayor mortalidad hospitalaria, 24,1% frente a 4,3% del segundo grupo. Los s\u00edntomas son la tr\u00edada: fiebre, tos y fiebre. Estos sujetos tend\u00edan a ser\u00a0<strong>hombres mayores con una mayor prevalencia de comorbilidades<\/strong>. <strong> Uno de cada 10 pacientes de este grupo requiri\u00f3 ingreso en UCI y una cuarta parte de ellos fallecieron<\/strong>,<\/p>\n\n\n\n<p class=\"has-normal-font-size wp-block-paragraph\">El segundo grupo fue el que registr\u00f3<strong>\u00a0menor porcentaje de ingreso en UCI y tasa de mortalidad<\/strong>. Estos presentaron<strong>\u00a0ageusia (dificultad para detectar el gusto) y anosmia (p\u00e9rdida de olfato),<\/strong>\u00a0a menudo acompa\u00f1adas de fiebre, tos o disnea.<\/p>\n\n\n\n<p class=\"has-normal-font-size wp-block-paragraph\">Respecto al\u00a0<strong>tercer grupo<\/strong>, tambi\u00e9n ten\u00eda artromialgia, es decir, dolor en articulaciones y\/o m\u00fasculos; dolor de cabeza y dolor de garganta, que a menudo tambi\u00e9n se acompa\u00f1a de fiebre, tos y\/o disnea. <strong>Casi el 11 % de ellos necesit\u00f3 UCI.<\/strong><\/p>\n\n\n\n<p class=\"has-normal-font-size wp-block-paragraph\">El cuarto tambi\u00e9n se manifest\u00f3 con diarrea, v\u00f3mitos y dolor abdominal, a menudo acompa\u00f1ados de fiebre, tos y\/o disnea. De estos,\u00a0<strong>el 8,5 % requiri\u00f3 ingreso en UCI y el 18,6 % falleci\u00f3<\/strong>. Esta tasa de mortalidad del grupo cuarto es la segunda m\u00e1s alta de los cuatro grupos identificados<\/p>\n\n\n\n<p class=\"has-text-align-center has-vivid-purple-color has-text-color has-normal-font-size wp-block-paragraph\"><strong>S\u00edntomas comunes<\/strong><\/p>\n\n\n\n<p class=\"has-normal-font-size wp-block-paragraph\">Los s\u00edntomas m\u00e1s comunes fueron fiebre (85,7 %), tos ( 75,8 %), disnea (59,7 %), artromialgia (31,4 %), diarrea (24,4 %), dolor de cabeza (11,6 %), dolor de garganta (9,9 %), ageusia o falta del gusto (8,2 %), v\u00f3mitos (7,4 %), anosmia o falta de olfato (7,3 %) y dolor abdominal (6,1 %).<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<p class=\"has-small-font-size wp-block-paragraph\">Noticia aparecida en <a href=\"https:\/\/www.redaccionmedica.com\/secciones\/sanidad-hoy\/coronavirus-sintomas-pronostico-uci-ingreso-neumonia-1650\">Redacci\u00f3n M\u00e9dica<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Los m\u00e9dicos internistas de la Sociedad Espa\u00f1ola de Medicina Interna (SEMI) han detectado cu\u00e1les son los s\u00edntomas que auguran un buen o mal pron\u00f3stico en la evoluci\u00f3n cl\u00ednica del paciente con COVID19. Los resultados preliminares han sido publicados en Journal of Clinical Medicine\u00a0bajo el t\u00edtulo\u00a0\u201cPredicting Clinical Outcome with Phenotypic Clusters in COVID-19 Pneumonia: An Analysis [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":2518,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[77,6],"tags":[],"class_list":["post-2517","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-covid19","category-investigacion"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\r\n<title>Coronavirus: cuatro fenotipos y su riesgo - Asociaci\u00f3n Galega de Lupus<\/title>\r\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\r\n<link rel=\"canonical\" href=\"https:\/\/lupusgalicia.org\/?p=2517\" \/>\r\n<meta property=\"og:locale\" content=\"es_ES\" \/>\r\n<meta property=\"og:type\" content=\"article\" \/>\r\n<meta property=\"og:title\" content=\"Coronavirus: cuatro fenotipos y su riesgo - Asociaci\u00f3n Galega de Lupus\" \/>\r\n<meta property=\"og:description\" content=\"Los m\u00e9dicos internistas de la Sociedad Espa\u00f1ola de Medicina Interna (SEMI) han detectado cu\u00e1les son los s\u00edntomas que auguran un buen o mal pron\u00f3stico en la evoluci\u00f3n cl\u00ednica del paciente con COVID19. Los resultados preliminares han sido publicados en Journal of Clinical Medicine\u00a0bajo el t\u00edtulo\u00a0\u201cPredicting Clinical Outcome with Phenotypic Clusters in COVID-19 Pneumonia: An Analysis [&hellip;]\" \/>\r\n<meta property=\"og:url\" content=\"https:\/\/lupusgalicia.org\/?p=2517\" \/>\r\n<meta property=\"og:site_name\" content=\"Asociaci\u00f3n Galega de Lupus\" \/>\r\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/LupusGalicia\/\" \/>\r\n<meta property=\"article:published_time\" content=\"2020-11-10T19:21:13+00:00\" \/>\r\n<meta property=\"article:modified_time\" content=\"2020-11-10T19:21:17+00:00\" \/>\r\n<meta property=\"og:image\" content=\"https:\/\/lupusgalicia.org\/wp-content\/uploads\/2020\/11\/medico-k7o-U601694551427aTG-624x385@Diario-Sur.jpg\" \/>\r\n\t<meta property=\"og:image:width\" content=\"622\" \/>\r\n\t<meta property=\"og:image:height\" content=\"385\" \/>\r\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\r\n<meta name=\"author\" content=\"Agal\" \/>\r\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\r\n<meta name=\"twitter:creator\" content=\"@LupusGalicia\" \/>\r\n<meta name=\"twitter:site\" content=\"@LupusGalicia\" \/>\r\n<meta name=\"twitter:label1\" content=\"Escrito por\" \/>\n\t<meta name=\"twitter:data1\" content=\"Agal\" \/>\n\t<meta name=\"twitter:label2\" content=\"Tiempo de lectura\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutos\" \/>\r\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/lupusgalicia.org\/?p=2517#article\",\"isPartOf\":{\"@id\":\"https:\/\/lupusgalicia.org\/?p=2517\"},\"author\":{\"name\":\"Agal\",\"@id\":\"https:\/\/lupusgalicia.org\/#\/schema\/person\/4c5a48f33530bf5afca090219ff56665\"},\"headline\":\"Coronavirus: cuatro fenotipos y su riesgo\",\"datePublished\":\"2020-11-10T19:21:13+00:00\",\"dateModified\":\"2020-11-10T19:21:17+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/lupusgalicia.org\/?p=2517\"},\"wordCount\":480,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/lupusgalicia.org\/#organization\"},\"image\":{\"@id\":\"https:\/\/lupusgalicia.org\/?p=2517#primaryimage\"},\"thumbnailUrl\":\"https:\/\/lupusgalicia.org\/wp-content\/uploads\/2020\/11\/medico-k7o-U601694551427aTG-624x385@Diario-Sur.jpg\",\"articleSection\":[\"Covid19\",\"Investigaci\u00f3n\"],\"inLanguage\":\"es\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/lupusgalicia.org\/?p=2517#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/lupusgalicia.org\/?p=2517\",\"url\":\"https:\/\/lupusgalicia.org\/?p=2517\",\"name\":\"Coronavirus: cuatro fenotipos y su riesgo - 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