{"id":212,"date":"2014-03-24T11:36:12","date_gmt":"2014-03-24T11:36:12","guid":{"rendered":"http:\/\/lupusgalicia.org\/?p=212"},"modified":"2014-03-24T11:36:58","modified_gmt":"2014-03-24T11:36:58","slug":"varios-factores-aumentan-riesgo-cardiaco-en-les","status":"publish","type":"post","link":"https:\/\/lupusgalicia.org\/?p=212","title":{"rendered":"Varios factores aumentan riesgo card\u00edaco en LES"},"content":{"rendered":"<h1 style=\"text-align: center;\"><span style=\"color: #800080;\">La clase social , la ascendencia y la medicaci\u00f3n son factores de riesgo card\u00edaco en los pacientes con lupus<\/span><\/h1>\n<div id=\"article_date\">Una nueva investigaci\u00f3n publicada en <strong><em>Rheumatology\u00a0<\/em><\/strong>revista cient\u00edfica internacional, ha sugerido que el lupus\u00a0eritematoso sist\u00e9mico (LES) en los pacientes de origen africano y de grupos socioecon\u00f3micos m\u00e1s bajos se enfrentan a un mayor riesgo de enfermedad cardiaca primaria.\u00a0Sin embargo, aquellos que toman medicamentos contra la malaria tienden a reducir su riesgo.<\/div>\n<div>\n<p>La investigaci\u00f3n encontr\u00f3 que el 14% de los pacientes experimentan problemas card\u00edacos como consecuencia de la enfermedad autoinmune a los cinco a\u00f1os del diagn\u00f3stico.\u00a0Tambi\u00e9n sugiere que factores particulares pueden aumentar o reducir el riesgo de pericarditis, enfermedad de v\u00e1lvulas card\u00edacas, \u00a0arritmias, miocarditis y endocarditis.<\/p>\n<p>Se usaron registros de una cohorte internacional de m\u00e1s de 1.400 pacientes de 34 centros de nueve pa\u00edses de Am\u00e9rica Latina. El estudio sigui\u00f3 a los pacientes que fueron reci\u00e9n diagnosticados con SLE entre 1997 y 2005.\u00a0La investigaci\u00f3n identific\u00f3 que los de ascendencia africana y los de grupos socioecon\u00f3micos m\u00e1s bajos tienen un mayor riesgo de problemas card\u00edacos, con un ratio de riesgo de 1,82 y 1,80 respectivamente. Ya hab\u00eda datos de una \u00a0investigaci\u00f3n \u00a0en el Reino Unido que\u00a0tambi\u00e9n ve\u00eda como la ascendencia africana era un factor de riesgo de problemas card\u00edacos en los pacientes con LES.<\/p>\n<p>Los problemas card\u00edacos pueden surgir en cualquier momento durante el curso del LES, pero <span style=\"text-decoration: underline;\">el g\u00e9nero<\/span> (hombre o mujer), l<span style=\"text-decoration: underline;\">a edad de inicio<\/span> de la enfermedad <span style=\"text-decoration: underline;\">y la educaci\u00f3n no se asociaron con un mayor riesgo.<\/span><\/p>\n<p><strong><span style=\"color: #800080;\">Los que est\u00e1n siendo tratados con medicamentos contra la malaria<\/span> <\/strong>tambi\u00e9n se encontr\u00f3 que ten\u00edan <strong><span style=\"color: #800080;\">un menor riesgo,<\/span><\/strong> con una ratio de riesgo de 0,49.<\/p>\n<p>La investigaci\u00f3n concluye: \u00a0<strong><em>\u00abLa m\u00e1s notable observaci\u00f3n del presente estudio fue el reconocimiento de que<span style=\"text-decoration: underline; color: #800080;\"> el uso de medicamentos contra la malaria<\/span> tiene un <span style=\"text-decoration: underline; color: #800080;\">efecto protector <\/span>sobre la aparici\u00f3n posterior de la enfermedad cardiaca primaria . \u00a0Este hallazgo ampl\u00eda la <span style=\"text-decoration: underline;\"><span style=\"color: #800080; text-decoration: underline;\">lista de los efectos beneficiosos de los antimal\u00e1ricos<\/span><\/span> en el lupus, pues<span style=\"text-decoration: underline; color: #800080;\"> adem\u00e1s ayuda a controlar la actividad de la enfermedad, las erupciones, el da\u00f1o global, la supervivencia renal y la mortalidad \u00ab<\/span><\/em><\/strong>.<\/p>\n<p><span style=\"text-decoration: underline;\">Bernardo Pons-Estel,<\/span> investigador jefe del estudio, dijo: \u00ab<em>Teniendo en cuenta que los medicamentos antipal\u00fadicos est\u00e1n disponibles en todo el mundo a un costo relativamente modesto, este hallazgo es muy relevante. \u00a0Adem\u00e1s, es importante se\u00f1alar que, dado que algunas de las manifestaciones cardiovasculares son silentes, \u00a0los m\u00e9dicos deber\u00edan investigar sistem\u00e1ticamente mediante pruebas no invasivas y sensibles, para que puedan ser tratados adecuadamente.\u00bb<\/em><\/p>\n<p><span style=\"text-decoration: underline;\">Dr. Chris Deighton<\/span>, presidente de la Sociedad Brit\u00e1nica de Reumatolog\u00eda, dijo: \u00abEsto nos recuerda que las enfermedades que los reumat\u00f3logos cuidan afectan mucho m\u00e1s all\u00e1 que las articulaciones, los m\u00fasculos y los huesos; tambi\u00e9n pueden afectar a \u00f3rganos vitales como el coraz\u00f3n. \u00a0Ciertos pacientes con lupus parecen ser m\u00e1s propensos a padecer que pero el tratamiento de la inflamaci\u00f3n subyacente\u00a0y de la alteraci\u00f3n inmunitaria puede marcar una gran diferencia para la salud general de estos pacientes. Todos los pacientes con lupus deben estar bajo la vigilancia permanente de un<strong> equipo multidisciplinario de reumatolog\u00eda<\/strong> \u00ab.<\/p>\n<p>Noticia aparecida en Medical News Today <a href=\"http:\/\/www.medicalnewstoday.com\/releases\/274147.php\">MDT<\/a><\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<div id=\"article_tabs\">\n<p><a href=\"http:\/\/translate.googleusercontent.com\/translate_c?act=url&amp;depth=1&amp;hl=es&amp;ie=UTF8&amp;prev=_t&amp;rurl=translate.google.es&amp;sl=en&amp;tl=es&amp;u=http:\/\/www.rheumatology.org.uk\/&amp;usg=ALkJrhgXt1wSHQKErRq0ef2ozXzmslcsyA\" target=\"_blank\">Sociedad Brit\u00e1nica de Reumatolog\u00eda<\/a><\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>La clase social , la ascendencia y la medicaci\u00f3n son factores de riesgo card\u00edaco en los pacientes con lupus Una nueva investigaci\u00f3n publicada en Rheumatology\u00a0revista cient\u00edfica internacional, ha sugerido que el lupus\u00a0eritematoso sist\u00e9mico (LES) en los pacientes de origen africano y de grupos socioecon\u00f3micos m\u00e1s bajos se enfrentan a un mayor riesgo de enfermedad cardiaca [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[14,6],"tags":[44,16],"class_list":["post-212","post","type-post","status-publish","format-standard","hentry","category-estudios","category-investigacion","tag-estudios","tag-tratamientos"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - 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